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 View Full-text : Current Issue |
| Case reports |
Korean J Intern Med. 2010
June;25(2):213-216.
DOI: 10.3904/kjim.2010.25.2.213
Two Lung Masses with Different Responses to Pemetrexed
Kwang Young Park, Jae Wook Jung, Seung Bum Nam, Ho Jin Lee, Hyo Seok Kim, Yoon Hee Choi, and Jae Cheol Lee
Department of Internal Medicine, Korea Cancer Center Hospital, Seoul, Korea |
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similar good response to initial chemotherapy with gemcitabine and carboplatin, the response to pemetrexed as a second-line treatment was different after re-growth of the tumors. These two lung masses could have originated from different clones or they could have progressed through different paths of molecular pathogenesis after metastasis, which would lead to different tumor characteristics, including their chemosensitivity. Regardless of their pathogenetic mechanisms, it seems important to recognize that tumors with the same histology that develop in one patient can have different responses to drugs. (Korean J Intern Med 2010;25:213-216)
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Keywords : Lung neoplasms; Pemetrexed; Neoplasms, multiple primary; Drug resistance |
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eISSN 2005-6648
