The Korean Journal of INternal Medicine
eISSN 2005-6648
pISSN 1226-3303
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Case reports
Korean J Intern Med. 2010 June;25(2):217-220.
DOI: 10.3904/kjim.2010.25.2.217

A Case of Diabetic Neuropathy Combined with Guillain-Barre Syndrome
Heung-Yong Jin, Kyung-Ae Lee, So-Young Kim, Ji-Hyun Park, Hong-Sun Baek, and Tae-Sun Park

Division of Endocrinology & Metabolism, Department of Internal Medicine, Chonbuk National University Medical School, Jeonju, Korea
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A 59-year-old man was admitted with numbness, pain, and a tingling sensation in both lower legs. He was initially diagnosed with diabetic peripheral neuropathy based on a symptom questionnaire and a quantitative sensory test. Despite symptomatic treatment of diabetic neuropathy, he complained of worsening sensory symptoms and additional motor weakness in both lower extremities. As the motor weakness of both extremities became more aggravated over time, brain and spine imaging tests and a nerve conduction test were performed. The nerve conduction study revealed motor and sensory axonal neuropathy. In his cerebrospinal analysis, albumino-cytologic dissociation, which is compatible to the Gillian-Barre syndrome, was found. Cerebrospinal fluid analysis showed albumino-cytologic dissociation. He was treated with intravenous immunoglobulin and his neurologic deficits were gradually improved. (Korean J Intern Med 2010;25:217-220)
Keywords : Diabetes mellitus; Guillain-Barre syndrome; Diabetic neuropathy
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